Artículos recientemente publicados

A continuación, se presentan los artículos científicos publicados en el periodo 2020-2021 por investigadores del Laboratorio de HLA:

1. Ramos-Martínez E, Rojas-Serrano J, Andrade W, Rojas-Bernabé A, Falfán-Valencia R, Pérez-Rubio G, Campos-Gutiérrez RI, Cruz-Pantoja R, Velasco-Medina A, Velázquez-Sámano G. Molecular analysis of phenotypic interactions of asthma. Cytokine. 2021 Apr 10:155524. doi: 10.1016/j.cyto.2021.155524. PMID: 33849767.
2. Bravo-Gutiérrez OA, Falfán-Valencia R, Ramírez-Venegas A, Sansores RH, Ponciano-Rodríguez G, Pérez-Rubio G. Lung damage caused by heated tobacco products and electronic nicotine delivery systems: a systematic review. Int J Environ Res Public Health 2021, 18, 4079. https://doi.org/10.3390/ijerph18084079.
3. Pérez-Rubio G, Falfán-Valencia R, Fernández-López JC, Ramírez-Venegas A, Hernández-Zenteno RDJ, Flores-Trujillo F, Silva-Zolezzi I. Genetic factors associated with COPD depend on the ancestral Caucasian/Amerindian component in the Mexican population. Diagnostics (Basel). 2021;11(4):599. doi: 10.3390/diagnostics11040599. PMID: 33801584
4. Fricke-Galindo I, Falfán-Valencia R. Genetics insight for COVID-19 susceptibility and severity: a review. Front Immunol. 2021 Apr 1;12:622176. doi: 10.3389/fimmu.2021.622176. PMID: 33868239.
5. Fricke-Galindo I, Falfán-Valencia R. Pharmacogenetics approach for the improvement of COVID-19 treatment. Viruses. 2021;13(3):413. doi: 10.3390/v13030413. PMID: 33807592
6. Ponce-Gallegos MA, González-Pérez MI, Mejía M, Nava-Quiroz KJ, Pérez-Rubio G, Buendía-Roldán I, Ramos-Martínez E, Rojas-Serrano J, Falfán-Valencia R. Single nucleotide polymorphism in the IL17A gene is associated with interstitial lung disease positive to anti-Jo1 antisynthetase autoantibodies. Life (Basel). 2021 ;11(2):174. https://doi: 10.3390/life11020174. PMID: 33672430
7. Pérez-Rubio G, Ponce-Gallegos MA, Domínguez-Mazzocco BA, Ponce-Gallegos J, García-Ramírez RA, Falfán-Valencia R. Role of the Host Genetic Susceptibility to 2009 Pandemic Influenza A H1N1. Viruses. 2021;13(2):344. https://doi.org/10.3390/v13020344. PMID: 33671828
8. Ocaña-Guzman R, Tellez-Navarrete NA, Preciado-Garcia M, Ponce-Gallegos MA, Buendia-Roldan I, Falfán-Valencia R, Chavez-Galan L. Multidrug-resistant tuberculosis patients expressing the HLA-DRB1*04 allele, and after treatment they show a low frequency of HLA-II+ monocytes and a chronic systemic inflammation. Microb Pathog. 2021 Feb 11:104793. doi: 10.1016/j.micpath.2021.104793. PMID: 33582220.
9. Juge PA, Lee j, Lau J, Kawano-Dourado L, Rojas Serrano J, Sebastiani M, Koduri G, Matteson E, Bonfiglioli K, Sawamura M, Kairalla R, Cavagna L, Bozzalla Cassione E, Manfredi A, Mejia M, Rodríguez-Henriquez P, González-Pérez M, Falfán-Valencia R, Buendía-Roldán I, Pérez-Rubio G, Ebstein E, et al. Methotrexate and Rheumatoid Arthritis associated Interstitial Lung Disease. Eur Respir J. 2021;57(2):2000337. doi: 10.1183/13993003.00337-2020. PMID: 32646919.
10. Ponce-Gallegos MA, Ramos-Martínez E, García-Carmona A, Mejía M, Nava-Quiroz KJ, Pérez-Rubio G, Ambrocio-Ortiz E, González-Pérez MI, Buendía-Roldán I, Rojas-Serrano J, Falfán-Valencia R. Genetic susceptibility to Antisynthetase Syndrome associated with single-nucleotide variants in the IL1B gene that lead variation in IL-1β serum levels. Front. Med. 2020;7:547186. doi: 10.3389/fmed.2020.547186. PMID: 33330522
11. Ponce-Gallegos MA, Ruiz-Celis A, Ambrocio-Ortiz E, Pérez-Rubio G, Ramírez-Venegas A, Bautista-Félix NE, Falfán-Valencia R. Polymorphisms in Processing and Antigen Presentation-Related Genes and Their Association with Host Susceptibility to Influenza A/H1N1 2009 Pandemic in a Mexican Mestizo Population. Viruses (Basel). 2020;12(11):E1224. doi: 10.3390/v12111224. PMID: 33138079
12. Ortega-Martínez A, Pérez-Rubio G, Ambrocio-Ortiz E, Nava-Quiroz K, Hernández-Zenteno R, Abarca-Rojano E, Rodríguez-Llamazares S, Hernández-Pérez A, García-Gómez L, Ramírez-Venegas A, Falfán-Valencia R. The SNP rs13147758 in the HHIP gene is associated with COPD susceptibility, serum and sputum protein levels in smokers. Front. Genet. 2020; 11:882;1-12. doi.org/10.3389/fgene.2020.00882 PMID: 33193570
13. Ortega-Martínez A, Pérez-Rubio G, Ramírez-Venegas A, Ramírez-Díaz ME, Cruz-Vicente F, Martínez-Gómez ML, Ramos-Martínez E, Abarca-Rojano E, Falfán-Valencia R. Participation of HHIP Gene Variants in COPD Susceptibility, Lung Function, and Serum and Sputum Protein Levels in Women Exposed to Biomass-Burning Smoke. Diagnostics (Basel). 2020;10(10):E734. doi: 10.3390/diagnostics10100734. PMID: 32977420
14. Lira-Lucio JA, Falfán-Valencia R, Ramírez-Venegas A, Buendía-Roldán I, Rojas-Serrano J, Mejía M, Pérez-Rubio G. Lung Microbiome Participation in Local Immune Response Regulation in Respiratory Diseases. Microorganisms 2020, 8, 1059; doi:10.3390/microorganisms8071059 PMID: 32708647.
15. Pérez-Rubio G, Ambrocio-Ortiz E, López-Flores LA, Juárez-Martín AI, Jiménez-Valverde LO, Zoreque-Cabrera S, Galicia-Negrete G, Ramírez-Díaz ME, Cruz-Vicente F, Castillejos-López MJ, Salinas-Lara C, Hernández-Zenteno RJ, Ramírez-Venegas A, Falfán-Valencia R. Heterozygous genotype rs17580 AT (PiS) in SERPINA1 is associated with COPD secondary to biomass-burning and tobacco smoking. A case-control and populational study. Int J COPD 2020:15 1181–1190. doi.org/10.2147/COPD.S247446.
16. Ramos-Martínez E, Falfán-Valencia R, Pérez-Rubio G, Mejia M, Buendia-Roldán I, González-Pérez MI, Mateos-Toledo HN, Rojas-Serrano J. Anti-Aminoacyl Transfer-RNA-Synthetases (Anti-tRNA) Autoantibodies Associated With Interstitial Lung Disease: Pulmonary Disease Progression Has a Persistent Elevation of the Th17 Cytokine Profile. J Clin Med 2020;9(5):E1356. doi: 10.3390/jcm9051356. PMID: 32384594.
17. Ambrocio-Ortiz E, Galicia-Negrete G, Pérez-Rubio G, Escobar Morales AJ, Abarca-Rojano E, Del Angel-Pablo AD, Castillejos-López M, Falfán-Valencia R. Single nucleotide and copy-number variants in IL4 and IL13 are not associated with asthma susceptibility or inflammatory markers: A case-control study in a Mexican-mestizo population. Diagnostics (Basel). 2020;10(5):E273. doi: 10.3390/diagnostics10050273. PMID: 32366038.
18. Buendía-Roldán I, Santiago-Ruiz L, Pérez-Rubio G, Mejia M, Rojas-Serrano J, Ambrocio-Ortiz E, Benítez-Valdez G, Selman M, Falfán-Valencia R. A major genetic determinant of autoimmune diseases is associated with the presence of autoantibodies in Hypersensitivity Pneumonitis. Eur Respir J. Aug 2020, 56 (2): 1901380. doi.org/10.1183/13993003.01380-2019. PMID: 32366487.
19. Falfán-Valencia R, Ramírez-Venegas A, Pérez Lara-Albisua JL, Ramírez-Rodriguez SL; Márquez-García JE, Buendía-Roldan I, Gayosso-Gómez LV, Pérez-Padilla R, Ortiz-Quintero B. Smoke exposure from chronic biomass burning induces distinct accumulative systemic inflammatory cytokine alterations compared to tobacco smoking in healthy women. Cytokine. 2020;131:155089. doi: 10.1016/j.cyto.2020.155089. PMID: 32283440. IF: 3.078 ISSN: 1043-4666.
20. Cartujano-Barrera, F, Rodríguez-Bolaños R, Arana-Chicas E, Gallegos-Carrillo K, Flores YN, Pérez-Rubio G, Falfán-Valencia R, Ellerbeck EF, Reynales-Shigematsu LM, Cupertino AP. Enhancing Nicotine Replacement Therapy use and adherence through a mobile intervention: Secondary data analysis of a single-arm feasibility study in Mexico. Tob Induc Dis. 2020;18:36. doi: 10.18332/tid/120076. PMID: 32395099.
21. Del Angel-Pablo AD, Buendía-Roldán I, Mejía M, Pérez-Rubio G, Nava-Quiroz KJ, Rojas-Serrano J, Falfán-Valencia R. Anti-HLA Class II Antibodies Correlate with C-Reactive Protein Levels in Patients with Rheumatoid Arthritis Associated with Interstitial Lung Disease. Cells 2020, 9 (3), 691; doi:10.3390/cells9030691. PMID: 32168865.
22. González-Pérez MI, Mejía-Hurtado JG, Pérez-Román DI, Buendía-Roldán I, Mejía M, Falfán-Valencia R, Mateos Toledo HN, Rojas-Serrano J. Evolution of Pulmonary Function in a Cohort of Interstitial Lung Disease Patients Positive to Antisynthetase Antibodies (ASAB). J Rheumatol. 2020;47(3):415-423. doi: 10.3899/jrheum.181141. PMID: 31203227.
23. Ponce-Gallegos MA, Pérez-Rubio G, Ambrocio-Ortiz E, Partida-Zavala N, Hernández-Zenteno R, Flores-Trujillo F, García-Gómez L, Hernández-Pérez A, Ramírez-Venegas A, Falfán-Valencia R. Genetic variants in IL17A and serum levels of IL-17A are associated with COPD related to tobacco smoking and biomass burning. Sci Rep. 2020;10(1):784. doi: 10.1038/s41598-020-57606-6. PMID: 31964947.
24. Ambrocio-Ortiz E, Pérez-Rubio G, Ramírez-Venegas A, Hernández-Zenteno R, Del Angel-Pablo AD, Pérez-Rodríguez ME, Salazar-Martínez AM, Abarca-Rojano E, Falfán-Valencia R. Effect of SNPs in HSP family genes in the genetic susceptibility to COPD secondary to tobacco smoking and biomass-burning smoke exposure, variation in the mRNA and intracellular Hsp levels. Front. Genet. 2020;10:1307. doi.org/10.3389/fgene.2019.01307 PMID: 31993068.
25. Del Ángel-Pablo AD, Juárez-Martín AI, Pérez-Rubio G, Ambrocio-Ortiz E, López-Flores LA, Camarena AE, Falfán-Valencia R. HLA allele and haplotype frequencies in three urban Mexican populations: genetic diversity for the approach of genomic medicine. Diagnostics (Basel). 2020; 10: E47. doi:10.3390/diagnostics10010047 PMID: 31963191 IF: 2.489 ISSN: 2075-4418.
26. Pavón-Romero GF, Pérez-Rubio G, Ramírez-Jiménez F, Ambrocio-Ortiz E, Merino-Camacho CR, Falfán-Valencia R, Teran LM. IL10 rs1800872 Is Associated with Non-Steroidal Anti-Inflammatory Drugs Exacerbated Respiratory Disease in Mexican-Mestizo Patients. Biomolecules 2020; 10: 104; doi:10.3390/biom10010104. PMID: 31936183
27. Pérez-Rubio G, García-Carmona S, García-Gómez L, Hernández-Pérez A, Ramírez-Venegas A, López-Flores LA, Sansores R, Falfán-Valencia R. The VNTR 48 bp Polymorphism in the DRD4 Gene Is Associated with Higher Tobacco Smoking in Male Mexican Mestizo Smokers with and without COPD. Diagnostics (Basel). 2020;10:E16. doi:10.3390/diagnostics10010016 PMID: 31905892.
28. Ponce-Gallegos MA, Pérez-Rubio G, García-Carmona A, García-Gómez J, Hernández-Zenteno R, Ramírez-Venegas A, Falfán-Valencia R. Haplotype in SERPINA1 (AAT) is Associated with Reduced Risk for COPD in a Mexican Mestizo Population. Int J Mol Sci. 2020; 21(1), 195. doi:10.3390/ijms21010195 PMID: 31892136.
29. Velasco-Torres Y, Ruiz Victor, Montaño M, Pérez-Padilla R, Falfán-Valencia R, Pérez-Ramos J, Pérez-Bautista O, Ramos C. Participation of the miR-22-HDAC4-DLCO Axis in Patients with COPD by Tobacco and Biomass. Biomolecules. 2019;9(12):E837. doi: 10.3390/biom9120837. PMID: 31817742 IF: 4.694. ISSN: 2218-273X